Author

Karsten Ruscher

Lund UniversityORCID 0000-0001-7211-2499Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Claire S. DurrantiD· 1 shared Ílknur ÖzeniD· 1 shared Michael P. ColemaniD· 1 shared Olivia SheppardiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Claire S. DurrantORCID

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1 paper

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedFeb 6, 2020

Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signaling

Claire S. Durrant, Karsten Ruscher, Olivia Sheppard…·Ílknur Özen

This study shows that BACE1 inhibition reduces excessive vascular sprouting in AD by restoring NOTCH3 signaling and normalizing endothelial filopodia formation.

46 citationstop 5%

mouseexperimental assay

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