Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health
Andrés Aranda-Díaz, Eric Neubauer Vickers, Kathryn Murie, Brian Palmer, Nicholas J. Hathaway, Inna Gerlovina, Simone Salvador Boene, Manuel II García-Ulloa, Pau Cisteró, Thomas Katairo, Francis D Semakuba, Bienvenu Nsengimaana, Hazel B. Gwarinda, Carla García-Fernández, William Louie, , Bryan Greenhouse
The paper develops MAD4HatTeR, an amplicon sequencing panel and analysis pipeline for detecting Plasmodium falciparum diversity, resistance markers, and gene duplications/deletions, showing high sensitivity and reproducibility across settings.
Scientific Reports · Mar 28, 2025Peer-reviewedGenomics