Kathryn Murie

PfPHAST: Plasmodium falciparum Public Health Amplicon Sequencing Tool, a Streamlined Panel for Malaria Genomic Surveillance

PfPHAST is a streamlined amplicon sequencing panel for malaria genomic surveillance, offering better quality control and cost efficiency than MAD4HatTeR without sacrificing performance on shared targets.

The Portable Microhaplotype Object and Tools

The paper introduces a standardized format for storing phased targeted sequencing data and provides tools to create and manipulate this format.

Classification of outcomes in antimalarial therapeutic efficacy studies with Aster

The paper introduces Aster, a statistical framework for accurately classifying antimalarial drug efficacy outcomes by accounting for complexity of infection and genotyping limitations.

Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health

The paper develops MAD4HatTeR, an amplicon sequencing panel and analysis pipeline for detecting Plasmodium falciparum diversity, resistance markers, and gene duplications/deletions, showing high sensitivity and reproducibility across settings.