Author

Yanying Guo

BGI ResearchORCID 0000-0001-7228-5656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chuanyu LiuiD· 1 shared Deqi CheniD· 1 shared Fan Zhu· 1 shared Feng ZhangiD· 1 shared Francis Ka-Ming ChaniD· 1 shared Haopeng LiniD· 1 shared Haoran TaoiD· 1 shared Hui ZengiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Chuanyu LiuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedDec 21, 2025

Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism

Haopeng Lin, Xin Liu, Feng Zhang…·Huisheng Liu

This study identifies PKM1-regulated PEP metabolism as a key factor in improving functional maturation of human stem-cell derived β cells by enhancing calcium response and insulin secretion.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 16, 2025

Single cell resolved spatial immune repertoire unveils spatial heterogeneity of lymphoid aggregates in human immune disorders

Xiaojuan Zhan, Yi Liu, Yanying Guo…·Yu Feng

This study introduces Stereo-XCR-seq, a method for in situ single-cell T and B cell repertoire sequencing, revealing spatial heterogeneity in lymphoid aggregates in immune disorders.

5 citations

humanscRNA-seq

𝕏 PostBluesky