Comprehensively Testing the Function of Missense Variation in the STK11 Tumour Suppressor
Daniel Zimmerman, Atina G. Coté, Warren van Loggerenberg, Marinella Gebbia, Nishka Kishore, Jochen Weile, Roujia Li, Chloe Reno, Ashley P.L. Marsh, Felicia Hernandez, Preksha Shahagadkar, Lauren Grove, Samuel R. Meier, Hsin‐Jung Wu, Silvia Fenoglio, , Frederick P. Roth
This study functionally tests STK11 missense variants in mammalian cells, identifying pathogenic variants and providing insights for clinical interpretation.
bioRxiv · Jul 14, 2025 · PreprintCancer Biology