Author

Chloe Reno

University of TorontoORCID 0009-0009-9332-0831Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant effect prediction· 2 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Atina G. CotéiD· 2 shared Frederick P. RothiD· 2 shared Marinella GebbiaiD· 2 shared Mikko TaipaleiD· 2 shared Warren van LoggerenbergiD· 2 shared Abbye E. McEweniD· 1 shared Ahmad Kamal HamidiD· 1 shared Airi HosokaiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Atina G. CotéORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 23, 2026

A scalable approach to resolving variants of uncertain significance

Malvika Tejura, Y P Chen, Abbye E. McEwen…·Lea M. Starita

The paper develops a scalable workflow to reclassify variants of uncertain significance using experimental and predictive evidence, resolving 75% of VUS in 40 genes.

4 citations

humanwhole-exome sequencing

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Cancer BiologybioRxivPreprintJul 14, 2025

Comprehensively Testing the Function of Missense Variation in the STK11 Tumour Suppressor

Daniel Zimmerman, Atina G. Coté, Warren van Loggerenberg…·Frederick P. Roth

This study functionally tests STK11 missense variants in mammalian cells, identifying pathogenic variants and providing insights for clinical interpretation.

DOI 10.1101/2025.07.14.664734

humanexperimental assay

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