Author

Silvia Fenoglio

Tango Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant effect prediction· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Hsin‐Jung WuiD· 2 shared Lauren Grove· 2 shared Samuel R. MeieriD· 2 shared Alan HuangiD· 1 shared Alborz BejnoodiD· 1 shared Andrew J. WatersiD· 1 shared Annabel Devault· 1 shared Ashley H Choi· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Hsin‐Jung WuORCID

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2 papers

Recent·Most cited

Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens

Silvia Fenoglio, Yi Yu, James Tepper, Lauren Grove, Alborz Bejnood, Samuel R. Meier, Ashley H Choi, Hsin‐Jung Wu, Annabel Devault, Shangtao Liu, Binzhang Shen, Tenzing Khendu, Hannah Stowe, Esther C. H. Uijttewaal, Minjie Zhang, , Teng Teng

This paper introduces CRISPR-StAR, an in vivo CRISPR screening platform with improved normalization and analysis tools, showing it can identify tumor suppressor gene effects not observable in vitro.

Cell Reports Methods · Jun 1, 2026Peer-reviewedGenomics

Comprehensively Testing the Function of Missense Variation in the STK11 Tumour Suppressor

Daniel Zimmerman, Atina G. Coté, Warren van Loggerenberg, Marinella Gebbia, Nishka Kishore, Jochen Weile, Roujia Li, Chloe Reno, Ashley P.L. Marsh, Felicia Hernandez, Preksha Shahagadkar, Lauren Grove, Samuel R. Meier, Hsin‐Jung Wu, Silvia Fenoglio, , Frederick P. Roth

This study functionally tests STK11 missense variants in mammalian cells, identifying pathogenic variants and providing insights for clinical interpretation.

bioRxiv · Jul 14, 2025 · PreprintCancer Biology