Ian D. Bentley

The paper measures miR-146a levels in different fluid samples from ventilated patients and finds that lower levels in alveolar space correlate with mortality, while plasma levels do not.

This study identifies Annexin A2 as a regulator of surfactant function during injurious ventilation, showing its role in maintaining surfactant composition and preventing lung stiffness in ARDS.

The paper uses scRNA-seq to identify unique macrophage and monocyte populations in a murine model of ozone-induced asthma exacerbation, linking them to inflammatory pathways and bronchial constriction.