PathologybioRxivPreprint
Chronic kidney disease exacerbates hyperlipidemia and atherosclerosis via miR-148a-3p targeting SIK1/AMPKα1 in liver
Yuzhi Huang, Ting Li, Erwei Hu…·Juan Zhou
This study identifies miR-148a-3p as a key mediator of CKD-induced hyperlipidemia and atherosclerosis by targeting SIK1/AMPK1 in the liver via exosomal transfer.
DOI 10.1101/2025.10.08.681287