Haoyu Wu

This study shows that obesity increases atherosclerosis through an inter-tissue miR-30e-SLC7A11 axis, where adipose-derived miR-30e-5p targets SLC7A11 in vascular endothelial cells, leading to metabolic and functional impairments.

This study identifies miR-148a-3p as a key mediator of CKD-induced hyperlipidemia and atherosclerosis by targeting SIK1/AMPK1 in the liver via exosomal transfer.

The paper identifies gene regulatory differences between primary human hepatocytes and organoid-derived hepatocytes using integrative omics analysis.

The paper identifies epigenetically silenced RNA-binding proteins in malaria hypnozoites and proposes they regulate dormancy and reactivation.

This study identifies an autocrine role for Hedgehog signaling in regulating epithelial cell proliferation and differentiation in the trachea.

This paper introduces a microfluidic platform for standardized, sensitive ChIP-Seq on low-input samples, enabling high-throughput and reproducible epigenetic profiling.

The paper shows Zbtb24 binding prevents promoter methylation and maintains gene activity in mouse embryonic stem cells.