Florian Wolf

The paper identifies 18 cell types in sponges, including neuroid cells with synaptic gene expression, suggesting early neuro-immune system evolution.

scGen models single-cell perturbation responses across cell types, studies, and species using variational autoencoders and latent space arithmetics, showing accurate out-of-sample predictions.

K-Branches detects branching points in single-cell data by clustering and model selection, identifying subgroups associated with differentiation events.