Cancer BiologybioRxivPreprint
Pulsed low-dose-rate radiation (PLDR) reduces the tumor-promoting responses induced by conventional chemoradiation in pancreatic cancer-associated fibroblasts
Janusz Franco‐Barraza, Tiffany Luong, Jessica Karen Wong…·Edna Cukierman
This study shows that pulsed low-dose-rate radiation combined with chemotherapy shifts pancreatic cancer-associated fibroblasts from tumor-promoting to tumor-suppressing, reducing desmoplasia and improving neoadjuvant therapy.
DOI 10.1101/2024.01.13.575510