Author
Daniel A. Peterson
Rosalind Franklin University of Medicine and ScienceORCID 0000-0001-7275-6403Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2022-2025 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 25 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- NeurosciencebioRxivPreprint
Mitochondrial Dysfunction in Alzheimer's Disease Is Driven By Excess ER-Calcium Release in Patient-Derived Neurons
Sarah Mustaly-Kalimi, Wacey Gallegos, Robert A. Marr…·Grace E. Stutzmann
This study shows that excess ER-Ca2+ release via RyR contributes to mitochondrial dysfunction in AD neurons, leading to cellular pathology and that pharmacological inhibition of RyR-Ca2+ release can reverse these effects.
1 citation - NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease
Sarah Mustaly-Kalimi, Wacey Gallegos, Robert A. Marr…·Grace E. Stutzmann
This study identifies calcium dysregulation via RyR as a driver of lysosomal dysfunction and protein aggregation in Alzheimer's disease, showing that dantrolene can restore proteolytic activity in AD models.