Jacques‐Olivier Pers

This study integrates multi-omics data from Sjogren's disease patients to identify LPA and metabolic pathway signatures in B cells and the immune microenvironment.

The paper identifies five SNPs in the DDX6-CXCR5 locus associated with autoimmune diseases and shows their functional effects on gene regulation in immune and epithelial cells.

This study evaluates molecular pathways in four spontaneous lupus mouse models and compares them to human SLE to assess translational relevance and guide future research.

BiomiX automates multiomics data analysis and integration, enabling efficient comparison of two cohorts through MOFA and providing interpretable results using literature and clinical data.

This study identifies novel genetic drivers in Sjogrens Syndrome through an integrative multi-omics approach, revealing epigenetic signatures and regulatory variants associated with the disease.