Adi Livnat

The paper presents a simulation model demonstrating nonrandom, non-Lamarckian mutation in evolution using an estimation-of-distribution algorithm, highlighting the role of internal genomic information integration.

The paper measures de novo mutation rates of the APOL1 G1 1024A[->]G mutation in Africans and Europeans, finding it has the highest rate and is more common in Africans where it provides adaptive benefit.