Michael Bright Yakass

Thymidine kinase-expressing yellow fever 17D reporter virus facilitates prodrug activation and bioorthogonal labelling of infected cells

This study develops a yellow fever 17D reporter virus expressing thymidine kinase to enable prodrug activation and bioorthogonal labeling of infected cells for tracking viral replication and tissue tropism.

De novo rates of a Trypanosoma-resistant mutation in two human populations

The paper measures de novo mutation rates of the APOL1 G1 1024A[->]G mutation in Africans and Europeans, finding it has the highest rate and is more common in Africans where it provides adaptive benefit.