BiochemistrybioRxivPreprint
Re-Engineering P(V) Chemical Warfare: Harnessing Stereogenic Phosphorus-Azoles for Protein Ligand Discovery In Vivo
R. Justin Grams, Olivia L. Murtagh1, Madeleine L. Ware…·Ku‐Lung Hsu
The paper develops PhAzE chemistry to selectively target serine hydrolases in vivo with minimal toxicity, demonstrating the potential of stereogenic P(V) compounds for protein ligand discovery.
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