Xianbin Tian

The paper identifies that splenic red pulp macrophages, aided by natural antibodies and complement, clear liver-resistant Streptococcus pneumoniae from the bloodstream in mice.

This study identifies natural antibodies that enable Kupffer cells to capture and kill encapsulated bacteria in the liver, offering a potential therapeutic approach for septic bacterial diseases.

This study shows influenza virus weakens neutrophil capture of low-virulence Streptococcus pneumoniae by reducing capsule receptor-mediated complement activation, enhancing bacterial survival and virulence.