Molecular BiologyGenome MedicinePeer-reviewed
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA
Ekaterina Pisareva, Lucia Mihalovičová, Brice Pastor…·Alain Roger Thierry
This paper demonstrates that neutrophil extracellular traps (NETs) are a major source of mono-N cirDNA independent of apoptosis, and shows that NE and MPO contribute to NET autocatabolism and cirDNA release.
50 citations