Author

Alexander Kloosterman

Karolinska InstitutetORCID 0000-0001-7345-110XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:database / resource· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:non-human primate· 1

Frequent Co-Authors

Björn HögbergiD· 2 shared Igor BaarsiD· 2 shared Alexander LindbergiD· 1 shared Björn ReiniusiD· 1 shared Boxuan SheniD· 1 shared Douglas A. MitchelliD· 1 shared Eduardo AlmansaiD· 1 shared Eve SeuntjensiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioengineering

Björn HögbergORCID

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4 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 11, 2026

A combinatorial DNA origami platform for biologically replicable, thermostable data storage and molecular authentication

Ferenc Fördős, Alexander Kloosterman, Alexander Lindberg…·Björn Högberg

This paper introduces DOCS, a DNA origami-based data storage system that enables biologically replicable, thermostable, and randomly accessible data storage and molecular authentication.

DOI 10.64898/2026.06.08.730396

DNA methylationexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintDec 9, 2024

Z-chromosome dosage compensation and sex-specific long non-coding RNAs in octopus

Natali Papanicolaou, Sebastian Wettersten, Alexander Kloosterman…·Björn Reinius

This study identifies Z-chromosome dosage compensation and sex-specific long non-coding RNAs in octopus, revealing evolutionary conservation of dosage compensation mechanisms.

DOI 10.1101/2024.12.09.627507

non-human primatebulk RNA-seq

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BioinformaticsNature Computational SciencePeer-reviewedJan 22, 2024

An error correction strategy for image reconstruction by DNA sequencing microscopy

Alexander Kloosterman, Igor Baars, Björn Högberg

This paper introduces an error correction method for DNA microscopy to improve spatial reconstruction accuracy by addressing spurious crosslinks and fused nodes.

11 citations

spatial transcriptomicsexperimental assay

𝕏 PostBluesky

BioinformaticsmSystemsPeer-reviewedAug 31, 2020

RRE-Finder: A Genome-Mining Tool for Class-Independent RiPP Discovery

Alexander Kloosterman, Kyle E. Shelton, Gilles P. van Wezel…·Douglas A. Mitchell

RRE-Finder identifies RRE domains across RiPP biosynthetic gene clusters, discovering novel classes and providing a dataset for further biochemical study.

111 citationstop 1%

protein sequencestatistical model

𝕏 PostBluesky