BioengineeringbioRxivPreprint
Computational Stabilization of the Human VH Germline Repertoire to Enable Conditional Multi-Specific Therapeutic Development
David F. Thieker, Jayd Hanna, Pricilla White…·Stephen J. Demarest
The paper develops a computational platform to stabilize human VH domains for creating multispecific biologics with conditional activity.
DOI 10.1101/2025.10.31.685826