Author

Linus Sandegren

Uppsala UniversityORCID 0000-0001-7382-9782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Greta ZaborskytėiD· 2 shared Birgitta LytsyiD· 1 shared Karin HjortiD· 1 shared Marie WrandeiD· 1 shared Patrícia CoelhoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

Greta ZaborskytėORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedApr 10, 2026

Rapid evolution of Klebsiella pneumoniae biofilms in vitro delineates adaptive changes selected during infection

Greta Zaborskytė, Patrícia Coelho, Marie Wrande, Linus Sandegren

This study evolves K. pneumoniae biofilms in vitro to identify adaptive changes linked to infection, finding convergent mutations affecting capsule, fimbriae, and c-di-GMP pathways.

4 citations

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivFeb 6, 2024

Convergent within-host evolution alters key virulence factors in a Klebsiella pneumoniae clone during a large hospital outbreak

Greta Zaborskytė, Karin Hjort, Birgitta Lytsy, Linus Sandegren

This study tracks the evolution of a Klebsiella pneumoniae clone during a hospital outbreak, identifying convergent genetic changes linked to virulence factors and niche adaptation.

DOI 10.1038/s41467-025-64521-9

bacteria (other)whole-genome sequencing

𝕏 PostBluesky