ImmunologybioRxivPreprint
ADAR1 haploinsufficiency and sustained viral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi-system interferonopathy
Caitlin M. Miller, James H. Morrison, Laura Bankers…·Eric M. Poeschla
The paper shows that ADAR1 haploinsufficiency combined with viral RdRp dsRNA synthesis causes dysregulated RNA editing and multi-system interferonopathy.
DOI 10.1101/2025.01.21.634124