Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Non-canonical immune response to the inhibition of DNA methylation via stabilization of endogenous retrovirus dsRNAs
Yongsuk Ku, Joo‐Hwan Park, Ryeongeun Cho…·Yoosik Kim
The paper identifies dsRNA-binding proteins that mediate decitabine's effects by stabilizing ERV RNAs, showing low Stau1 and TINCR expression correlates with poor treatment outcomes in AML patients.
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