Ahmed Abdelmonem Hemedan

The paper describes the development and evaluation of an agentic framework using LLMs to explore molecular interaction maps through user-driven prototyping and testing.

This study uses Boolean modeling on PD cohorts to show sex-specific miRNA dysregulation affects mitochondrial biogenesis, mitophagy, and autophagy in Parkinson's disease.

This paper constructs and compares computational disease maps of ulcerative colitis and atopic dermatitis to identify shared and unique molecular mechanisms and potential therapeutic targets.

The paper presents the ISD map, an interactive resource modeling molecular mechanisms of psoriasis and atopic dermatitis, and identifies potential therapeutic targets through hypothesis generation.

This study uses Boolean models to analyze Parkinson's disease progression and identifies subtype-specific regulatory modules and biomolecules.

This study uses Boolean modeling to analyze Parkinson's disease mechanisms, identify drug targets, and simulate treatment responses using the PD-map framework.

The paper presents a computational framework for analyzing SARS-CoV-2-host interactions to identify drug targets and model disease mechanisms.