Saumya Jain

The paper shows that the L2/3 continuum in the mouse visual cortex develops through two phases: a genetically programmed initial phase and a visually experience-driven second phase.

The paper uses spatial transcriptomics and computational methods to show that vision affects both cell state and cell type composition in the visual cortex during critical periods.

The paper shows that the Ecdysone pathway regulates timing of transcription factor expression, which in turn controls cell-type specific wiring programs in fly neurons.