Ke Yan Wen

This paper designs bacterial computers using spatial diffusion and engineered Escherichia coli to perform digital logic operations and complex computations.

The paper constructs acetoacetate-sensitive whole-cell biosensors using the AtoSC two-component system and demonstrates their functionality in E. coli.

FlopR calibrates and normalizes flow cytometry and plate reader data using a unified R package, validated on E. coli GFP expression data to identify subpopulations from bulk measurements.