NeuroscienceProgress in NeurobiologyPeer-reviewed
Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system
Paulino Ramirez, Gabrielle Zuniga, Wenyan Sun…·Bess E Frost
This study shows that pathogenic tau accelerates transposable element activation in the aging mouse brain, particularly ERVs, suggesting a link between tauopathy and transposable element-induced neurotoxicity.
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