Molecular BiologybioRxivPreprint
Protein Phosphatase PP1 Regulation of Pol II Phosphorylation is Linked to Transcription Termination and Allelic Exclusion of VSG Genes and TERRA in Trypanosomes.
Rudo Kieft, Yang Zhang, Haidong Yan…·Robert S. Sabatini
This study shows that PP1-1 modulates Pol II termination in T. brucei by dephosphorylating the Pol II large subunit, leading to readthrough transcription and pervasive genome transcription.
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