Cancer BiologybioRxivPreprint
Single CAR-Dual target: Intracranial Delivery of Anti-PD-L1 CAR T Cells Effectively Eradicates Glioma and Immunosuppressive Cells in the Tumor Microenvironment.
María José Ulloa-Navas, Yan Luo, Jesus Emiliano Sanchez-Garavito…·Alfredo Quiñones‐Hinojosa
This study develops a PD-L1-targeting CAR T cell therapy, MC9999, which effectively eradicates glioblastoma and immunosuppressive cells in the tumor microenvironment through intracranial delivery.
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