Totipotency and high plasticity in an embryo with a stereotyped, invariant cleavage program
Amber Q. Rock, Mansi Srivastava
This paper investigates totipotency and plasticity in the acoel Hofstenia miamia, showing that isolated 4-cell stage macromeres can form whole organisms and that 8-cell stage blastomeres can reprogram to develop into a hatchling worm.