Bayesian genome scale modelling identifies thermal determinants of yeast metabolism
Gang Li, Yating Hu, Jan Zrimec, Hao Luo, Hao Wang, Aleksej Zelezniak, Boyang Ji, Jens Nielsen
This paper uses Bayesian modeling to identify temperature-dependent enzymes in yeast metabolism, revealing squalene epoxidase as a key rate-limiting enzyme and demonstrating its role in thermotolerance.
Nature Communications · Jan 8, 2021Peer-reviewedSystems Biology