Se Hoon Kim

This study identifies developmental meningeal mosaicism as the origin of human meningiomas, showing that driver mutations are present in phenotypically normal meninges and shared across tumors.

This study identifies glial progenitor cells as the cell-of-origin for IDH-mutant gliomas by analyzing patient tissues and mouse models.

This paper develops MethylInsight, a platform that adapts CNS tumor classification frameworks to whole-genome methylation data, achieving high accuracy comparable to array-based methods.

This study identifies 69 mutated genes in malformations of cortical development using multiomic profiling of 317 brain resections and single-cell sequencing.

The paper shows JICD1 forms a transcriptional complex with DDX17, SMAD3, and TGIF2 to increase SOX2 expression, promoting cancer stem cell properties and tumorigenicity.