Author

Christopher Zhang

Georgia Institute of TechnologyORCID 0000-0001-7522-2159Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Christopher Zhang1 paper · Carnegie Institution for Science

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Brian K. HammeriD· 3 shared William C. RatcliffiD· 2 shared Anthony BurnettiiD· 1 shared Eric LibbyiD· 1 shared Hayley HassleriD· 1 shared Isabel K. CalimlimiD· 1 shared Lauren SpeareiD· 1 shared Matthew D. HerroniD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersMicrobiology

Brian K. HammerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

41% of Gram-negative bacteria encode a Type Six Secretion System

Christopher Zhang, Hayley Hassler, William Ratcliff, Lauren Speare, Brian K Hammer

The paper quantifies T6SS prevalence in Gram-negative bacteria using genome analysis and finds it is present in 41% of well-sampled genera.

bioRxiv · Nov 9, 2026 · PreprintMicrobiology

Establishing genetic tractability in Jeongeupia sacculi HS-3: disruption of rpoS hinders biofilm formation

Zachary Beddingfield, Isabel K. Calimlim, Christopher Zhang, Brian K. Hammer

This study establishes genetic tractability in Jeongeupia sacculi HS-3 by disrupting rpoS, showing it regulates biofilm formation under low-nutrient conditions but not general stress survival.

bioRxiv · Oct 10, 2026 · PreprintMicrobiology

The fitness costs of reproductive specialization scale inversely with organismal size

Christopher Zhang, Eric Libby, Anthony Burnetti, Matthew D. Herron, William C. Ratcliff

The paper shows that the fitness costs of reproductive specialization decrease with organism size, using a population genetic framework and empirical data from algae.

Proceedings of the National Academy of Sciences · Apr 6, 2026Peer-reviewedEvolutionary Biology

Higher levels of antibiotic resistance are less competitive: the hidden ecological cost of no-metabolic cost resistance

Miles T. Wetherington, Raymond Copeland, Christopher Zhang, Brian K. Hammer, Peter J. Yunker

This study shows that highly antibiotic-resistant bacteria can inadvertently help susceptible strains survive, revealing an ecological cost to extreme resistance that limits its spread.

bioRxiv · Dec 15, 2025 · PreprintMicrobiology