Author

Hayley B. Hassler

Georgia Institute of TechnologyORCID 0000-0002-8920-5840Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Anton S. PetroviD· 1 shared Brian K HammeriD· 1 shared Christopher ZhangiD· 1 shared Claudia Álvarez-CarreñoiD· 1 shared Lauren SpeareiD· 1 shared Loren Dean WilliamsiD· 1 shared Tanisha Gupta· 1 shared William RatcliffiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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1 shared paperEvolutionary Biology

Anton S. PetrovORCID

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2 papers

Recent·Most cited

41% of Gram-negative bacteria encode a Type Six Secretion System

Christopher Zhang, Hayley Hassler, William Ratcliff, Lauren Speare, Brian K Hammer

The paper quantifies T6SS prevalence in Gram-negative bacteria using genome analysis and finds it is present in 41% of well-sampled genera.

bioRxiv · Nov 9, 2026 · PreprintMicrobiology

Deep shifts in Evolutionary Rate Trajectories of Ancient Bacterial Genes

Hayley B. Hassler, Tanisha Gupta, Anton S. Petrov, Loren Dean Williams, Claudia Álvarez-Carreño

The paper reconstructs evolutionary rate trajectories of 528 genes from the Last Bacterial Common Ancestor across 2.1 billion years, identifying four clusters with distinct patterns linked to gene function and environmental changes.

bioRxiv · Sep 10, 2026 · PreprintEvolutionary Biology