Inbal Goshen

This study shows that activating astrocytes in an Alzheimer's disease mouse model fully corrects memory deficits and even improves memory beyond wild-type levels.

The paper investigates how astrocyte Gq and Gi pathways modulate recent and remote memory recall by affecting CA1->ACC projection recruitment to engrams.

The paper investigates how engram stability and maturation change during systems consolidation, finding that CA1 engrams remain stable but new cells in remote recall engrams form through specific connectivity changes.

This study shows that hippocampal astrocytes in awake mice encode reward location in familiar environments through persistent calcium activity, which can be decoded to predict the mouse's position.

The paper characterizes hippocampal astrocytic domains and their spatial relationships to excitatory and inhibitory neurons using imaging and computational methods.

This study shows that astrocytes modulate hippocampal-cortical communication during learning, specifically impairing remote memory recall when manipulated.