NeurosciencebioRxivPreprint
Arf1-Ablation-Induced Neuronal Damage Promotes Neurodegeneration Through an NLRP3 Inflammasome-Meningeal γδ T cell-IFNγ-Reactive Astrocyte Pathway
Guohao Wang, Weiqin Yin, Hyun‐Hee Shin, Xianyu Steven Hou
This study identifies a pathway linking Arf1 ablation in neurons to neurodegeneration via microglia, astrocytes, and T cells in mice, with relevance to human diseases.
DOI 10.1101/2020.03.27.012526