Author

Guohao Wang

Kunming Institute of ZoologyORCID 0000-0002-9991-1765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Weiqin YiniD· 2 shared Bin Fang· 1 shared Bin ReniD· 1 shared Chang Yu· 1 shared Hongyu Chen· 1 shared Hyun‐Hee ShiniD· 1 shared Lianchao Gao· 1 shared Peixia Yu· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Weiqin YinORCID

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2 papers

Recent·Most cited

Sustained Relief of Chronic Pain via a Nav1.7_Targeting ASO_siRNA Conjugate

Bin Ren, Chang Yu, Weiqin Yin, Zhuangchuan Yuan, Hongyu Chen, Yicao Liu, Bin Fang, Suyuan Liu, Lianchao Gao, Zhiwei Cao, Qingqing Yu, Xin Qiu, Peixia Yu, Guohao Wang

This paper develops an ASO-siRNA conjugate that provides sustained pain relief by targeting Nav1.7, outperforming individual components and existing drugs in preclinical models.

bioRxiv · Mar 30, 2026 · PreprintNeuroscience

Arf1-Ablation-Induced Neuronal Damage Promotes Neurodegeneration Through an NLRP3 Inflammasome-Meningeal γδ T cell-IFNγ-Reactive Astrocyte Pathway

Guohao Wang, Weiqin Yin, Hyun‐Hee Shin, Xianyu Steven Hou

This study identifies a pathway linking Arf1 ablation in neurons to neurodegeneration via microglia, astrocytes, and T cells in mice, with relevance to human diseases.

bioRxiv · Mar 27, 2020 · PreprintNeuroscience