Author

Guillaume Walther

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementORCID 0000-0001-7604-8973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Amandine FalcoiD· 1 shared Ariane SultaniD· 1 shared Besma Abed· 1 shared Claire Fenech· 1 shared Corinne LeloupiD· 1 shared Cyril BreukeriD· 1 shared David NoccaiD· 1 shared Fabienne Liénard· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

Amandine FalcoORCID

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2 papers

Recent·Most cited

Obesity induces phenotypic switching of gastric smooth muscle cells through the activation of the PPARD/PDK4/ANGPTL4 pathway

Sanaa Dekkar, Kamilia Mahloul, Amandine Falco, Karidia Konate, Romane Pisteur, Sarah Maurel, Laurent Maı̈moun, Norbert Chauvet, Prisca Boisguérin, David Nocca, Ariane Sultan, Florian Pallot, Guillaume Walther, Nicolas Cénac, Cyril Breuker, , Pascal de Santa Barbara

This study identifies the PPARD/PDK4/ANGPTL4 pathway as a mechanism by which obesity induces phenotypic switching of gastric smooth muscle cells, leading to dysmotility.

Journal of Biomedical Science · Jul 12, 2025Peer-reviewedPhysiology

Non-Caloric Sweeteners combined with glucose affect hypothalamic glucose sensing-induced insulin secretion, food re-intake through neuronal cellular metabolism: An in vivo and in vitro approaches

J. Haydar, Claire Fenech, Fabienne Liénard, Besma Abed, Sylvie Grall, Loïc VE Briand, Guillaume Walther, Corinne Leloup

This study investigates how non-caloric sweeteners combined with glucose affect hypothalamic glucose sensing and insulin secretion in rats, showing reduced insulin release and increased food intake.

bioRxiv · Dec 16, 2024 · PreprintNeuroscience