Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis: Towards 1,000 Hz Speeds with 100% Ion Utilization Using High Resolution Ion Mobility Precursor Isolation
Daniel DeBord, Leonard C. Rorrer, Liulin Deng, Frederick G. Strathmann
This paper introduces high resolution ion mobility (HRIM) as a faster and more sensitive alternative to quadrupole mass spectrometry for fragmentation analysis, achieving up to 1,000 Hz speeds with 100% ion utilization.
bioRxiv · Oct 18, 2024 · PreprintBiochemistry