Leonard C. Rorrer

This paper introduces PAMAF, a novel DIA-MS mode using HRIM for proteomics, achieving higher sensitivity and efficiency in protein identification and quantification.

This study uses PAMAF mode HRIM-MS to quantify succinylation sites in mouse kidney, showing Sirt5 regulates succinylation of mitochondrial proteins involved in metabolism.

This paper introduces high resolution ion mobility (HRIM) as a faster and more sensitive alternative to quadrupole mass spectrometry for fragmentation analysis, achieving up to 1,000 Hz speeds with 100% ion utilization.