Author

Carola Dröge

Düsseldorf University HospitalORCID 0000-0001-7634-5134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Assay:organoid / primary culture· 1 Assay:protein sequence· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Amelie StalkeiD· 2 shared Annika BehrendtiD· 2 shared Holger GohlkeiD· 2 shared Verena KeiteliD· 2 shared Alex Bastianelli· 1 shared Daniel MulnaesiD· 1 shared Eva-Doreen Pfister· 1 shared Filip KoenigiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

Amelie StalkeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PhysiologybioRxivPreprintFeb 8, 2024

Impaired transitioning of the FXR ligand binding domain to an active state underlies an FXR-associated PFIC phenotype

Annika Behrendt, Alex Bastianelli, Jan Stindt…·Holger Gohlke

This study identifies a missense variant in FXR that impairs its conformational transition to an active state, leading to reduced BSEP expression and a PFIC phenotype.

DOI 10.1101/2024.02.08.579530

humanorganoid / primary culture

𝕏 PostBluesky

BioinformaticsbioRxivPreprintFeb 20, 2022

Vasor: Accurate prediction of variant effects for amino acid substitutions in MDR3

Annika Behrendt, Pegah Golchin, Filip Koenig…·Holger Gohlke

Vasor is a machine learning model that accurately predicts the pathogenicity of MDR3 missense variants, outperforming existing tools and providing a webserver for predictions.

1 citation

humanprotein sequence

𝕏 PostBluesky