Author

Alex Bastianelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Amelie StalkeiD· 1 shared Annika BehrendtiD· 1 shared Carola DrögeiD· 1 shared Eva-Doreen Pfister· 1 shared Holger GohlkeiD· 1 shared Jan Stindt· 1 shared Kathrin Grau· 1 shared Malte SgoddaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Amelie StalkeORCID

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1 paper

Recent·Most cited

Impaired transitioning of the FXR ligand binding domain to an active state underlies an FXR-associated PFIC phenotype

Annika Behrendt, Alex Bastianelli, Jan Stindt, Eva-Doreen Pfister, Malte Sgodda, Tobias Cantz, Sebastian Hook, Kathrin Grau, Stefanie Brands, Carola Dröge, Amelie Stalke, Michele Bonus, Sabine Franke, Ulrich Baumann, Verena Keitel, Holger Gohlke

This study identifies a missense variant in FXR that impairs its conformational transition to an active state, leading to reduced BSEP expression and a PFIC phenotype.

bioRxiv · Feb 8, 2024 · PreprintPhysiology