NeuroscienceStem Cell ResearchPeer-reviewed
Antisense oligonucleotide therapy rescues aggresome formation in a novel Spinocerebellar Ataxia type 3 human embryonic stem cell line.
Lauren R. Moore, Laura Keller, David D. Bushart…·Henry Lauris Paulson
This paper describes a novel SCA3 human embryonic stem cell line and shows that antisense oligonucleotides reduce ATXN3 aggregation and prevent aggresome formation.
42 citations