Author

Luca Torielli

University of PaviaORCID 0000-0001-7655-2037Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Federica GuarraiD· 1 shared Giorgio ColomboiD· 1 shared Hao ShaoiD· 1 shared Jason E. GestwickiiD· 1 shared Stefano Artin SerapianiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Federica GuarraORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedApr 3, 2025

How a pathogenic mutation impairs Hsp60 functional dynamics from monomeric to fully assembled states

Luca Torielli, Federica Guarra, Hao Shao…·Giorgio Colombo

This study uses molecular dynamics simulations to show that the V72I mutation in Hsp60 disrupts allosteric communication, rigidifying its complexes and impairing function.

15 citations

structural biologydeep learning

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