Michaela Hoffman

This study examines genetic and physiological changes in the mediodorsal thalamus of alcohol-dependent mice and finds alcohol-biased calcium signaling during choice behaviors.

The paper shows that alcohol drinking increases calcium activity in mouse central amygdala dynorphin-expressing neurons compared to other solutions.

The paper shows that prelimbic cortical neurons encode hedonic value during solution consumption, with distinct activity patterns for water, ethanol, and sucrose, and these patterns are altered by ethanol dependence.

This study identifies sex-specific changes in functional brain connectivity networks in mice with excessive alcohol drinking using whole-brain c-Fos mapping.

This study uses in vivo fiber photometry to monitor neural activity in mice and rats during exposure to drugs of abuse, revealing changes in calcium transients in brain regions associated with reward and decision-making.