John J. Woodward

This study examines genetic and physiological changes in the mediodorsal thalamus of alcohol-dependent mice and finds alcohol-biased calcium signaling during choice behaviors.

This study shows that targeting KV7 channels in the prefrontal cortex of alcohol-dependent mice can rescue cognitive deficits and reduce alcohol intake.

The paper identifies dysregulated proteins in the orbitofrontal cortex of individuals with alcohol use disorder using proteomics and machine learning, linking them to drinking behavior in mice.

This study identifies dense cortical input to the RMTg in rats, showing its role in aversive signaling and behavioral responses.

The paper shows that prelimbic cortical neurons encode hedonic value during solution consumption, with distinct activity patterns for water, ethanol, and sucrose, and these patterns are altered by ethanol dependence.

This study uses in vivo two-photon imaging to show chronic ethanol exposure alters sensory-evoked neuronal and vascular responses in mice, with region-specific neurovascular coupling changes.

This study shows that inhibiting the ventral hippocampus increases ethanol drinking in non-dependent mice but not in dependent mice, suggesting reduced vHC activity contributes to increased drinking.

This study uses in vivo fiber photometry to monitor neural activity in mice and rats during exposure to drugs of abuse, revealing changes in calcium transients in brain regions associated with reward and decision-making.

This study shows that CRF-R1 regulates VTA-GABAergic plasticity, which is suppressed by CB1 receptor inhibition after chronic alcohol exposure.

This study shows that neuronal responsiveness in mouse visual cortex increases with cortical depth, matching levels seen in other species, and suggests differences in V1 function between rodents and mammals.