Jennifer A. Rinker

This study examines genetic and physiological changes in the mediodorsal thalamus of alcohol-dependent mice and finds alcohol-biased calcium signaling during choice behaviors.

This study shows that targeting KV7 channels in the prefrontal cortex of alcohol-dependent mice can rescue cognitive deficits and reduce alcohol intake.

This paper develops a head-fixed ethanol self-administration model in mice, demonstrating reliable ethanol-seeking behavior and relapse-like reinstatement of lever pressing.

The paper shows that alcohol drinking increases calcium activity in mouse central amygdala dynorphin-expressing neurons compared to other solutions.

The paper shows that prelimbic cortical neurons encode hedonic value during solution consumption, with distinct activity patterns for water, ethanol, and sucrose, and these patterns are altered by ethanol dependence.

This study identifies a sex-dependent glutamatergic circuit from the paraventricular thalamus to BNST CRF neurons that modulates binge drinking and avoidance behavior.

This study identifies sex-specific changes in functional brain connectivity networks in mice with excessive alcohol drinking using whole-brain c-Fos mapping.

This study shows that inhibiting the ventral hippocampus increases ethanol drinking in non-dependent mice but not in dependent mice, suggesting reduced vHC activity contributes to increased drinking.

The paper identifies Kcnn3 as a pharmacogenetic target for reducing ethanol drinking and anxiety-like behaviors in stressed, ethanol-dependent mice.

This study uses in vivo fiber photometry to monitor neural activity in mice and rats during exposure to drugs of abuse, revealing changes in calcium transients in brain regions associated with reward and decision-making.