Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver Russell Syndrome-like mouse models
Suhee Chang, Diana B. Fulmer, Stella K. Hur, Joanne L. Thorvaldsen, Li Li, Yemin Lan, Eric A. Rhon‐Calderón, Nicolae Adrian Leu, Xiaowen Chen, Jonathan A. Epstein, Marisa S. Bartolomei
This study investigates the role of H19/Igf2 dysregulation in cardiac and placental defects in SRS-like mouse models, showing disrupted ECM and endothelial proliferation pathways.
eLife · Nov 16, 2022Peer-reviewedDevelopmental Biology