Stomatin-like protein 2 senses oxidative stress through the interaction with phosphatidic acid to promote mitochondrial unfolded protein response
Maria Paulina Castelo Rueda, Irene Pichler, Karolína Musilová, Stanislav Kmoch, Peter Paul Pramstaller, Aleš Hnı́zda, Andrew A. Hicks, Roman Vozdek
This study identifies STL-1/SLP-2 as a sensor of oxidative stress that activates the mitochondrial unfolded protein response through interaction with phosphatidic acid.
bioRxiv · Apr 30, 2024 · PreprintMolecular Biology